How many aces to give a horse orally?

Acepromazine (ACE) is a mild tranquilizer used as a pre-sedative in horse treatment. ACE is more susceptible and relaxing for horses than other anesthetics and sedatives. It is used when grooming horses, stitching wounds up, stopping wriggling, and doing small surgical operations. But how many aces to give a horse orally?

As per the recommendation of a certified vet, 2.5 ml acepromazine is required for a 500 kg horse. But this amount might change between 0.5 and 1.5 depending on the level of sedation. It would help if you had to take consultation with a vet before applying sedatives to your horse.

In this guide, we have discussed details on ace sedatives for horses. Also, you will know the dosage, side effects and precautions of using ACE on your horse. So, let’s know.

Usage of Acepromazine for horse

We know Acepromazine is a mild tranquilizers that keeps a temperamental horse calm. It is not always necessary to keep calm in your horse. But let’s know in which cases sedatives are used to calm the horse.

  • When a horse is injured, it is important to touch its body to perform the necessary tests. Sedatives are used in this case.
  • Ace sedatives keep the horse calm when minor operations are performed, or stitches are applied.
  • Acepromazine is also used to remove skin tumors, ocular surgery, dental operations and neurectomies.
  • Some vets suggest using ACE for laminitis because it lowers blood pressure and increases circulation at the hoof.
  • The grouchy horse is given ace as a sedative during deworming and grooming; otherwise, they do not allow deworming or grooming.

Dosage and Administration of acepromazine sedatives

Knowing about the proper dosage and Administration is important. Let’s know the ace tablet dosage and liquid dosage for horses. 

Procedure Dosage Concentration Period Duration
Oral 0.25-1.0 mg/lb. 10mg tablet Treatment N\A
Oral 0.25-1.0 mg/lb. 25mg tablet Treatment N\A
Intravenous injection 2-4 mg/100lb 10 mg/ml Treatment N\A
Intramuscular injection 2-4 mg/100lb 10 mg/ml Treatment N\A


What are the side effects of Acepromazine?

Many horses’ owners want to know the side Effects of acepromazine medication. However, side effects are rarely seen for using acepromazine tranquiliser, but there must be some side effects. Let’s know those. Retractor penis muscle can be paralyzed due to the use of acepromazine class tranquiliser. Therefore, caution should be exercised before administering this sedative to male horses. Besides, regardless of male and female horses, ace sedatives should apply with proper dosage. Otherwise, overdose can cause death or serious health issues.

Precautions for using Acepromazine for your horse

Precautions for using Acepromazine for your horse

  • Acepromazine might be responsible for nervous system depressants. Even the Sympathetic nervous system has seen into the horse.
  • Overdosage ace can cause motor restlessness, and it can be amplified in animals susceptible to treatment.
  • Acepromazine can increase the impact of general anesthesia in horses. So, it is recommended to be careful when applying ace as common anesthesia.
  • Additional care is required for that horse that is suffering from stress, debilitation, cardiac disease, or shock
  • Be careful to apply ace on horses which have liver dysfunction or leukopenia since it detoxifies in horse liver
  • rapid intravenous injection can occur hypertension which from cardiovascular collapse may also happen
  • the accidental intracarotid injection can often cause clinical sickness or death of your horse
  • it is not approved by the FDA, which means this sedative is prohibited by lawful written or oral order from a certified vet.

What do I need to do after my horse has been sedated with Acepromazine?

Acepromazine will not let your horse completely sleep. It will induce sleep and keep the horse calm in any situation. Your horse can remain silent or sleep after doing the necessary tasks of sedating. So, what should you do then? It would help if you left your horse in a calm environment. As the reaction to the sedative gradually wears off, your horse will return to normal at home.

Sedatives may take up to 7 hours to fully wear off. You should check your horse frequently during this period. Many often ask, ``Can you ride a horse on ace”? The answer is no. 

Give him plenty of water and food when he is normal in your home. At the same time, observe if there are any negative or fearful symptoms in your horse. If you notice anything wrong, consult a vet as soon as possible.


  • How long does oral ace take to work on horses?

There is no specific time for an ace to work on the horse. It depends on the dosage of Acepromazine and the types of horses. As each horse’s weight, physical condition and activity level are different, it is natural that their calm time will vary. But on average, an oral ace can take 30 to 60 minutes to start work on horses.

  • Can you overdose a horse on Acepromazine?

No, you can’t overdose a horse on Acepromazine because it would be poisonous. Oral ace overdose can cause sudden unconsciousness, collapse and seizures, coma, or even death. Besides, you may notice drowsiness and slowed breathing on your horse as the common symptoms of ace overdose. In case of an overdose, see a vet at home immediately and give the necessary treatment after emptying the stomach.

  • How long does ace last in the horse?

How long does ace stay in horses’ system? The lasting time of Acepromazine may vary depending on the horse’s physical condition and dosage level. However, on average, Acepromazine can last about one to four hours on a horse. Good to know that Acepromazine is a prohibited over-the-counter medication. So, it is best to be careful when applying aces to your horse.

Final word:

You must know how many aces to give a horse orally. We are repeating for your convenience that a 500 pounds horse can take 2.5 ml of Acepromazine orally at a time. On the contrary, this amount can fluctuate if the horse’s weight is much or less than 500 pounds. So, be careful about the amount of sedatives.

It is good to consult a vet before applying ace sedatives to your horse. Otherwise, your horse may get sick, or you can overdose your horse with an ace.

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